Synthesis of Celecoxib and Structural Analogs- A Review.
Celecoxib oral capsule is available as a generic drug and a brand-name drug. Brand name: Celebrex. Celecoxib only comes as a capsule you take by mouth. This drug is used to treat various forms of.Celecoxib (INN) is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis.Synthesis of Celecoxib Analogues Possessing a N-Difluoromethyl-1,2-dihydropyrid-2-one 5-Lipoxygenase Pharmacophore: Biological Evaluation as Dual Inhibitors of Cyclooxygenases and 5-Lipoxygenase.
Synonyms: Celecoxib Carboxylic Acid Methyl Ester; p-(5-(p-Methoxycarbonylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide Catalog No.: SA11308 More Details.Celecoxib is a non-steroidal, anti-inflammatory drug (NSAID) and a cyclooxygenase-2 (COX-2) selective inhibitor. Celecoxib is at least 10-20 times more selective for COX-2 over COX-1. Celecoxib is majorly bound to plasma proteins and is eliminated from liver via cytochrome P450 metabolic pathway. Celecoxib is recommended drug for the management.
Non-steroidal anti-inflammatory drugs (NSAIDs) are medicines that are widely used to relieve pain, reduce inflammation, and bring down a high temperature. They're often used to relieve symptoms of headaches, painful periods, sprains and strains, colds and flu, arthritis, and other causes of long-term pain.
